Korean J Dermatol.  2007 Sep;45(9):923-925.

A Case of Pseudoxanthoma Elasticum-Like Late-onset Focal Dermal Elastosis

• Seo JK
• Shim HS
• Jeong Y
• Lee SK

Abstract

Late-onset focal dermal elastosis is a recently described disorder afflicting elderly patients with yellow papules on the neck and flexural areas. Although there are similar clinical findings to pseudoxanthoma elasticum, no stigmata of pseudoxanthoma elastimum are not evident. Histologically the papules are characterized by increased elastic fibers of normal appearance in the mid and deep dermis and no evidence of solar elastosis. Late-onset focal dermal elastosis may be caused by focal accumulation of normal appearing elastic tissue due to loss of age related homeostatic growth regulating gene control mechanism. We report a case of pseudoxanthoma elasticum-like late-onset focal dermal elastosis and suggest that this condition may be more common than has been reported.

Keyword

Late-onset focal dermal elastosis; Pseudoxanthoma elasticum

MeSH Terms

Aged
Christianity
Dermis
Elastic Tissue
Humans
Neck
Pseudoxanthoma Elasticum