Korean J Infect Dis.  2002 Oct;34(5):349-353.

A Case of Malignant External Otitis with Pichia ohmeri

Affiliations
  • 1Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. jhsong@smc.samsung.co.kr

Abstract

Pichia ohmeri is a rare fungal pathogen for human infection. To date, only 5 cases of P. ohmeri infection have been reported including fungemia, disseminated infection and peritonitis. We report the first case of malignant external otitis and mastoid osteomyelitis caused by P. ohmeri. The patient had a long history of diabetes, hypertension and arrrhythmia. The patient was admitted to the hospital because of otorrhea, otalgia and hearing difficulty for 3 months. Internal auditory canal MRI showed osteomyelitis of left mastoid bone and skull base. Culture of ear discharge and bone biopsy specimen grew P. ohmeri. The patient had been treated with amphotericin-B followed by fluconazole.

Keyword

Pichia ohmeri; Malignant external otitis; Pathogen

MeSH Terms

Biopsy
Ear
Earache
Fluconazole
Fungemia
Hearing
Humans
Hypertension
Magnetic Resonance Imaging
Mastoid
Osteomyelitis
Otitis Externa*
Peritonitis
Pichia*
Skull Base
Fluconazole
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