Korean J Gastrointest Endosc.  1987 Nov;7(1):27-30.

Overview of Clinical Experience in the Treatment of Peptic Ulcer with Famotidine


The aim of the investigation was to study the efficacy and safety of Famotidine (Gaster), a new, potent, histamine H-receptor antagonist. The Famotidine (40 mg p.o.h.s) was administered to 22 patients with 33 peptic ulcers for 4 weeks. Follow up checking was done at 2 week and 4 week by endoscopy and physical examination. All patients were carefully evaluated at regular intervals for adverse drugh reactions by clinical and laboratory examinations. By the end of study, 97% of the ulcers were healed by endoscopically and rapid and complete relief of epigastric pain was observed in all patients. Famotidine treatment was well tolerated and no alterations in laboratory tests were noted. Therfore, Famotidine was proved effective in the treatment of peptic ulcers (especially multiple ulcers) and was well tolerted on the short-term basis.

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