Korean J Gastrointest Endosc.  1990 May;10(1):85-88.

A Case of Melanosis Coli

Abstract

Melanosis coli is the brownish pigmentation of the colon associted with the ingestion of anthraquinone compounds as iaxatives. The brownish discoloration of the colon mucosa is due to accumulation of macrophage containing lipofuscin pigment in the lamina propria. This is the one of the complications of laxative abuse, but the pigments disappear by withdrawing the anthraquinone. We report a case of malanosis coli histologically confirmed by fibersigmoidoscopic biopsy in a 70-year-old female patient consuming anthraquinone compound for twelve months with a review of the literature.


MeSH Terms

Aged
Biopsy
Colon
Eating
Female
Humans
Lipofuscin
Macrophages
Melanosis*
Mucous Membrane
Pigmentation
Lipofuscin
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