J Korean Ophthalmol Soc.  2013 Feb;54(2):265-271. 10.3341/jkos.2013.54.2.265.

Diurnal Variation of Subjective Visual Symptoms of Diabetic Patients

• Hong SJ
• Lee KM
• Sohn JH

• KMID: 2216662
• DOI: http://doi.org/10.3341/jkos.2013.54.2.265

Abstract

PURPOSE
To investigate the diurnal variation of subjective visual symptoms of diabetic patients and to evaluate its correlation with visual acuity, blood pressure, blood glucose and OCT-measured macular thickness.
METHODS
Fifty-five diabetic patients (56 eyes) who were hospitalized for the operation of the fellow eye were enrolled in the study. They underwent optical coherence tomography (OCT) measurements of macular thickness with retinal mapping protocol of OTI/SLO OCT at 5PM, 8PM on operation day, and at 7AM, 10AM on following day. Visual acuity (log MAR), refraction, intraocular pressure, blood glucose and blood pressure were also measured at each time. We surveyed the patients' symptomatic visual variation and its pattern if there is any change over a day.
RESULTS
Thirteen patients (25%) had reported changes in their subjective visual symptom over a day according to their blood glucose level. Among twenty-four cases with changes in their subjective visual acuity throughout the exam, only ten showed their real visual acuity change in accordance with their symptoms.
CONCLUSIONS
One fourth of our diabetic patients stated fluctuation in their vision according to their blood glucose level, but there were no correlations between visual acuity, blood glucose level and macular thickness.

Keyword

Diabetic retinopathy; Diurnal variation; Macular thickness; Optical coherence tomography; Visual symptom

MeSH Terms

Blood Glucose
Blood Pressure
Diabetic Retinopathy
Eye
Humans
Intraocular Pressure
Retinaldehyde
Tomography, Optical Coherence
Vision, Ocular
Visual Acuity
Blood Glucose
Retinaldehyde

Figure

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  Figure 1. Central subfield thickness, blood glucose, visual acuity, and blood pressure throughout the day from 7 AM to 8 PM.

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  Figure 2. Correlation between blood pressure change and best corrected visual acuity, letter score change. There was no correlation between two factors (correlation coefficient = −0.081, p = 0.295, Pearson correlation test).

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  Figure 3. Correlation between blood pressure change and retinal thickness change. There was no correlation between two factors (correlation coefficient = 0.098, p = 0.204, Pearson correlation test).

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  Figure 4. Correlation between retinal thickness and best-corrected visual acuity, letter score. They showed significant relationship between two factors. (A = all group, B = macula edema group, C = macula edema-free group).

Reference

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