J Korean Ophthalmol Soc.  2011 Dec;52(12):1519-1523. 10.3341/jkos.2011.52.12.1519.

A Case of Basosquamous Carcinoma of the Eyelid

• Yum HR
• Cho WK
• Paik JS
• Yang SW

• KMID: 2215159
• DOI: http://doi.org/10.3341/jkos.2011.52.12.1519

Abstract

PURPOSE
To report a rare case of basosquamous carcinoma of the eyelid, an aggressive tumor with a higher tendency for recurrence and metastasis.
CASE SUMMARY
An 87-year-old woman presented with a painful mass and bloody exudates at the left lateral lower eyelid. Four years previous, the patient was diagnosed with basosquamous carcinoma of the left lower eyelid after biopsy at another hospital. At that time, she was unable to receive operation because she had suffered from a serious heart condition. With time, the left lower eyelid mass continued to grow and symptoms and signs of pain and bloody exudates appeared. The patient underwent surgery for complete tumor resection and repair and the biopsy of a specimen showed tumor-free margins and no metastasis to distal sites.
CONCLUSIONS
Basosquamous carcinoma is a subtype of basal cell carcinoma with aggressive behavior and a higher tendency for recurrence and metastasis. However, our case showed no recurrence with no metastasis to the nearby lymph nodes, vessels, or nerves. We report a case of basosquamous carcinoma of the eyelid at old age that was cured after operative resection.

Keyword

Basosquamous carcinoma; Eyelid

MeSH Terms

Aged, 80 and over
Biopsy
Carcinoma, Basal Cell
Carcinoma, Basosquamous
Exudates and Transudates
Eyelids
Female
Heart
Humans
Lymph Nodes
Neoplasm Metastasis
Recurrence

Figure

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  Figure 1. Clinical appearance of the left eyelid lesion at initial presentation shows a 30 (horizontal) × 50 (vertical) × 15 (height) mm3 sized huge mass.

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  Figure 2. (A) Intraoperative photographs show a widely excised lesion. (B) Upper) 7 (horizontal) × 4 (vertical) × 1 (height) mm3 sized upper eyelid mass, Lower) 30 (horizontal) × 50 (vertical)× 15 (height) mm3 sized lower eyelid mass.

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  Figure 3. Hematoxylin and eosin staining of the excised lesion. (A) Low magnification view exhibits squamous differentiation in center of some nodules (arrow). (H & E staining, magnification ×100). (B) Basosquamous carcinoma has an aggressive-growth in-filtrative pattern with tongues of tumor cells embedded in dense stroma containing proplastic fibroblasts (arrow). (H & E staining, magnification ×200).

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  Figure 4. After 1 month, a postoperative photograph of the patient shows good healing and no recurrence of the tumor.

Reference

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