J Korean Ophthalmol Soc.  2008 Mar;49(3):479-486. 10.3341/jkos.2008.49.3.479.

Multifocal Electroretinography After Reattachment of Macula-Off Retinal Detachment

• Ahn JH
• Chang MH
• Kyung SE

• KMID: 2211322
• DOI: http://doi.org/10.3341/jkos.2008.49.3.479

Abstract

PURPOSE: To assess macular function by multifocal electroretinography after reattachment of macula-off retinal detachment and to evaluate relationship between duration of macular detachment (DMD) and functional recovery.
METHODS
Nineteen patients (19 eyes) with macula-off rhegmatogenous retinal detachment underwent pneumatic retinopexy or scleral buckling. Retinal reattachment was obtained successfully in all patients. Duration of follow-up of all patients is at least more than 12 months. Eyes were divided into 2 groups, corresponding to the DMD : Group A (within 7 days, n=9 eyes), Group B (>7 days, n=10 eyes). The amplitudes and implicit times of N1-wave and P1-wave of mfERGs in Area 1 (Ring 1), Area 2 (Ring 1+2) were compared between Group A and B and between Group A and control group.
RESULTS
The P1 amplitudes in Area 1 and 2 were significantly different between Group A and B (P<0.05). N1 amplitudes in Area 1 were significantly different between Group A and B (P<0.05), but no significant difference of P1 amplitudes in Area 2 between Group A and B (P>0.05). There were no significant difference of all data between Group A and control in Area 1 and 2 (P>0.05) The implicit times of N1, P1 were not significantly different between Group A and B.
CONCLUSIONS
The DMD plays a key role in recovery of visual function after reattachment. The mfERG is a useful tool to evaluate the recovery of macular function after reattachment of macula-off retinal detachments.

Keyword

Macular detachment; Multifocal electroretinography; Rhegmatogenous retinal detachment

MeSH Terms

Electroretinography
Eye
Follow-Up Studies
Humans
Retinal Detachment
Retinaldehyde
Scleral Buckling
Retinaldehyde

Figure

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  Figure 1. Stimulus array of 61 hexagonal elements; ring 1 (red) and ring 2 (blue) correspond to fovea and parafovea, respectively.

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  Figure 2. The typical waveform of the primary multifocal ERG response is a biphasic wave with initial negative deflection followed by a positive peak. There may be a second negative deflection after the peak. The preferred designation is to label these three peaks respectively N1, P1, and N2.

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  Figure 3. Comparison of P1 amplitudes of Group A, B, and control. The box-and-whiskers plots include the 25 th, 50 th, and 75 th percentiles. The whiskers define the minimum and maximum values. Figure 3A and 3B show data in Area 1 and 2, respectively.

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  Figure 4. Comparison of N1 amplitudes of Group A, B, and control. The box-and-whiskers plots include the 25 th, 50 th, and 75 th percentiles. Except for outliers, the whiskers define the minimum and maximum values. Figure 4A and 4B show data in Area 1 and 2, respectively.

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