J Korean Ophthalmol Soc.  2002 Sep;43(9):1664-1669.

The Effects of Needle Revision of Failed Filtering Blebs with Preoperative Mitomycin-C Application

• Kim JY
• Lee SH

Abstract

PURPOSE: The purpose of the study is to determine the efficacy and safety of needle revision of failed filtering blebs using preoperative mitomycin C (MMC) application.
METHODS
We reviewed the records of 28 patients (31 eyes) who had undergone needle revision with MMC for the treatment of failed filtering bleb. MMC (0.02 mg/ml, 0.1 ml) was injected subconjunctivally one day before needle revision.
RESULTS
Postopertive mean follow-up period was 42 weeks. Twenty five eyes (80.6%) were classified as surgical success which was defined as IOP less than 21 mmHg with or without any antiglaucomatous therapy. Intraocular pressure decreased from 25.5+/-6.0 mmHg before surgery to 18.6+/-5.2 mmHg at the last follow-up (p< 0.05). No serious complication was found.
CONCLUSION
Our result suggested that needle revision with the preoperative subconjunctival injetion of mitomycin-C may be an effective and safe method to revive failed filtration blebs.

Keyword

Failed filtering bleb; Mitomycin-C; Needle revision; Preoperative application

MeSH Terms

Blister*
Filtration
Follow-Up Studies
Humans
Intraocular Pressure
Mitomycin*
Needles*
Mitomycin