J Korean Ophthalmol Soc.  1988 Apr;29(2):279-289.

Electroretinographic Change after Intravitreal Silicone Oil Injection in Rabbit

• Chang K
• Lee J

Abstract

Effect of silicone oil in vitreous cavity of the rabbit was studied with electroretinogram. Pars plana vitrectomy was performed bilaterally in nine white rabbits, and they were divided into 3 groups. 1.6~1.7 cc of silicone oil was injected in right eye in 1st group, 0.8 cc of silicone oil was injected in right eye in 2 nd group, and 0.8~1.0 cc of silicone oil was injected in right eye after retinal tear was made in 3 rd group. Left eye in each group was used as a control. Photopic and scotopic electroretinographic studies were performed in both eye of rabbits preoperatively and postoperatively 2 days, 1 week, 2 weeks, 3 weeks, and 4 weeks. In each group, a and b-wave amplitude was decreased in silicone oil injected eye compared to control eye at postoperative 2 days, and was increased to normal amplitude at postoperative 4 weeks in both photopic and scotopic electroretinograms. Implicit time of a and b-wave was not affected in each group. Above results suggest that rabbit electroretinogram is not affected by intravitreal silicone oil until postoperative 4 weeks.

MeSH Terms

Rabbits
Retinal Perforations
Silicone Oils*
Vitrectomy
Silicone Oils