J Korean Soc Plast Reconstr Surg.  2002 May;29(3):221-224.

A Case of Dermatofibrosarcoma Protuberans in a Breast

• Lee PK
• Kim HT
• Kim YJ

Abstract

Dermatofibrosarcoma protuberans is a moderate degree malignant tumor that has high recurrent rate and low metastatic rate. This occurs most frequently on the trunk, the proximal part of upper limbs and lower limbs. However, the occurrence of this disease in the breast is extremely rare. Our case is a 20-years-old female patient who has a non-elevated nodule in the lower part of right breast. The mass was lobulated and relatively fixed to skin, but movable. The color of the overlying skin was reddish purple. The biopsy showed characteristic storiform pattern of the spindle cells on the H-E stain, and positive and negative stain on the immunohistochemical stain of anti-CD34 antibody and S-100 protein respectively. Based on the above findings we confirmed dermatofibrosarcoma protuberans (DFSP) and did wide excision for preventing recurrence and reconstructed the breast using a pedicled latissimus dorsi musculocutaneous flap. F-U taken 11 months after the operation shows no recurrence and good cosmetic result without deformity of breast or donor site morbidity.

Keyword

Dermatofibrosarcoma protuberans (DFSP); Breast; CD34

MeSH Terms

Biopsy
Breast*
Congenital Abnormalities
Dermatofibrosarcoma*
Female
Humans
Lower Extremity
Myocutaneous Flap
Recurrence
S100 Proteins
Skin
Superficial Back Muscles
Tissue Donors
Upper Extremity
S100 Proteins