J Korean Rheum Assoc.
2004 Mar;11(1):57-60.
A Case of Azathioprine Induced Recurrent Acute Pancreatitis in a Patient with Behcet's Disease
- Affiliations
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- 1Department of Internal Medicine, Division of Rheumatology, Kangnam St.Mary's Hospital, College of Medicine, The Catholic University of Korea. rapark@catholic.ac.kr
Abstract
- Acute pancreatitis is a serious disease with a fatality rate of up to 15%. Drugs are considered a rare cause of acute pancreatitis and azathioprine has been linked to subsequent acute pancreatitis in several case reports. We present a 48-year-old female who developed abdominal pain and elevation of serum amylase and lipase levels following azathioprine treatment for Behcet's disease. Abdominal CT scan reveals diffuse enlarged pancreas and large amount of fluid collection at peritoneal cavity. She was recovered with conventional therapy for acute pancreatitis and withdrawal of azathioprine. When the patient erroneously took the drug once again, acute pancreatitis was more rapidly developed than initial attack.
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