J Korean Rheum Assoc.  2006 Mar;13(1):1-9.

Treatment of Ankylosing Spondylitis

Affiliations
  • 1Division of Rheumatology, Department of Internal Medicine, The Hospital for Rheumatic Diseases, Hanyang University College of Medicine, Seoul, Korea. thkim@hanyang.ac.kr
  • 2Internal Medicine, Eulji University School of Medicine, Daejeon, Korea.

Abstract

The conventional approach to treatment of patients with ankylosing spondylitis (AS) have been rather limited in the last decades. Evidence is accumulating that tumor necrosis factor (TNF) blocker is highly effective in AS. This article reviews the most recent and the most pertinent advances in the treatment in AS. TNF blocker have been evaluated in a number of randomized controlled trials in AS and have been demonstrated to be effective in disease activity, function, and quality of life in these patients. TNF blocker is emerging as the best therapeutic option available for patients with AS.

Keyword

Ankylosing spodylitis; Treatment; Tumor necrosis factor blocker

MeSH Terms

Humans
Quality of Life
Spondylitis, Ankylosing*
Tumor Necrosis Factor-alpha
Tumor Necrosis Factor-alpha
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