J Korean Soc Transplant.  2006 Dec;20(2):258-260.

A Case of Merkel Cell Carcinoma in a Renal Transplant Patient

Affiliations
  • 1Department of Nephrology, Busan Paik Hospital, College of Medicine, Inje University, Korea. KYW8625@chollian.net
  • 2Department of Pathology, Busan Paik Hospital, College of Medicine, Inje University, Korea.
  • 3Department of Plastic Surgery, Busan Paik Hospital, College of Medicine, Inje University, Korea.
  • 4Department of Internal Medicine, Bong Seng Hospital, Busan, Korea.

Abstract

Merkel cell carcinoma (MCC) is a rare, frequently lethal, primary neuroendocrine carcinoma of the skin. Histopathologically, it appears as a dermal nodule of small undifferentiated malignant cells. Historically, MCC was considered to be an eccrine carcinoma. Recognition of its neuroendocrine features later led to the hypothesis that it arose from Merkel cells in the skin, although recent evidences revisit the question of an epithelial origin. We recently experienced a Mercel cell carcinoma. So, we report a MCC case originated from skin in renal transplant patient who was administrated immunosuppressive agent.

Keyword

Renal transplantation; Merkel cell carcinoma; Tacrolimus

MeSH Terms

Carcinoma, Merkel Cell*
Carcinoma, Neuroendocrine
Humans
Kidney Transplantation
Merkel Cells
Skin
Tacrolimus
Tacrolimus
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