J Korean Radiol Soc.  1999 May;40(5):865-870. 10.3348/jkrs.1999.40.5.865.

Pulmonary Epithelioid Hemangioendothelioma: Radiologic Findings

Affiliations
  • 1Department of Radiology, Seoul National University College of Medicine and the Institute of Radiation Medicine, SNUMRC, Korea.
  • 2Department of Pathology, Seoul National University College of Medicine, Korea.
  • 3Department of Radiology, Asan Medical Center, College of Medicine, University of Ulsan, Korea.
  • 4Department of Radiology, Yonsei University College of Medicine, Korea.
  • 5Department of Radiology, Yeungnam University of Medicine, Korea.
  • 6Department of Radiology, Boramae Hospital, Korea.

Abstract

PURPOSE: To describe the computed tomographic (CT) findings and follow-up changes of pulmonary epithelioidhemangioendothelioma (PEH).
MATERIALS AND METHODS
The clinical and serial radiological findings [follow-up,5months-5 years (mean, 26.4 months)] of five patients with histologically proven PEH were retrospectivelyreviewed. Three were men and two were women, and they were aged between 25 and 54(mean, 35.6) years. Initial chestradiographs were available in all cases and HRCT, conventional CT and MRI were available in one, respectively.Follow-up conventional CT (n=3) and HRCT (n=2) were performed, and the size, number and distribution of thenodules, calcification and follow-up changes were analyzed.
RESULTS
In four patients, chest radiography and CTrevealed bilateral multiple nodules 1-15mm in size. In two patients, the nodules showed interstitial distribution,and one had a single nodule in the right upper lobe. On follow-up CT images, an endobronchial mass withobstructive pneumonitis (n=1) or consolidation with pleural effusion (n=1) was noted. In three patients, thenodules had increased in size and number, and calcification within the nodules was observed in two.
CONCLUSION
PEH usually manifests as widespread nodules, sometimes with calcification. Along with larger and increased numbersof nodules, follow-up images of PEH may show an endobronchial mass with obstructive pneumonitis or aconsolidation-like mass with pleural effusion.

Keyword

Lung neoplasms, CT

MeSH Terms

Female
Follow-Up Studies
Hemangioendothelioma, Epithelioid*
Humans
Magnetic Resonance Imaging
Male
Pleural Effusion
Pneumonia
Radiography
Thorax
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