J Korean Neurosurg Soc.  2015 Sep;58(3):192-196. 10.3340/jkns.2015.58.3.192.

Angiographic and Clinical Factors Related with Good Functional Outcome after Mechanical Thrombectomy in Acute Cerebral Artery Occlusion

• Park JH
• Han YM
• Jang KS
• Yoon WS
• Jang DK
• Park SK

• KMID: 2191358
• DOI: http://doi.org/10.3340/jkns.2015.58.3.192

Abstract

OBJECTIVE
The aim of this study is to investigate good prognostic factors for an acute occlusion of a major cerebral artery using mechanical thrombectomy.
METHODS
Between January 2013 to December 2014, 37 consecutive patients with acute occlusion of a major cerebral artery treated by mechanical thrombectomy with stent retrievers were conducted. We analyzed clinical and angiographic factors retrospectively. The collateral flow and the result of recanalization were sorted by grading systems. Outcome was assessed by National Institutes of Health Stroke Scale (NIHSS) and modified Rankin Scale (mRS) at 90 days. We compared the various parameters between good and poor angiographic and clinical results.
RESULTS
Twenty seven patients demonstrated good recanalization [Thrombolysis in Cerebral Infarction (TICI) 2b or 3] after thrombectomy. At the 90-day follow up, 19 patients had good (mRS, 0-2), 14 had moderate (3-4) and four had poor outcomes (5-6). The mRS of older patients (> or =75 years) were poor than younger patients. Early recanalization, high Thrombolysis in Myocardial Infarction risk score, and low baseline NIHSS were closely related to 90-day mRS, whereas high TICI was related to both mRS and the decrease in the NIHSS.
CONCLUSION
NIHSS decreased markedly only when recanalization was successful. A good mRS was related to low initial NIHSS, good collateral, and early successful recanalization.

Keyword

Acute cerebral artery occlusion; Functional outcome; Mechanical recanalization; Prognostic factor; Stent retriever

MeSH Terms

Cerebral Arteries*
Cerebral Infarction
Follow-Up Studies
Humans
Myocardial Infarction
National Institutes of Health (U.S.)
Retrospective Studies
Stents
Stroke
Thrombectomy*

Figure

• 

  Fig. 1 Angiographic and clinical outcome after recanalization. TICI : Thrombolysis in Cerebral Infarction, mRS : modified Rankin Scale, NIHSS : National Institutes of Health Stroke Scale.

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