J Korean Med Assoc.  2011 Feb;54(2):156-160. 10.5124/jkma.2011.54.2.156.

Impacts of climate change on aeroallergens

  • 1Department of Allergy and Rheumatology, Ajou University School of Medicine, Suwon, Korea. hspark@ajou.ac.kr


Climactic changes are key environmental issues affecting allergic diseases. Temperature and CO2 content have been found to be increasing together with climate changes, which could increase pollen production, extend the pollination period, and augment the allergenic components of major pollens. Changes in the distribution of major trees and weeds have been noted. Severe weather events such as thunderstorm winds and precipitation could increasingly cause pollen grains to burst, releasing allergenic particles and leading to extensive mold growth. Air pollutants can increase the concentration of allergen released from pollen grains and allow for easier penetration into airway mucosa. Future studies will be essential to investigate the mechanisms by which allergenic contents can be changed in response to climate change. A better understanding of how aeroallergens interact with air pollutants is needed. Climate change has a significant impact on aeroallergen levels and content in ways which may accelerate the development of allergic diseases. Future strategies will be crucial in preventing the allergic diseases associated with climate changes.


Climate change; Aeroallergens; Allergic disease; Pollen; Fungi

MeSH Terms

Air Pollutants
Climate Change
Mucous Membrane
Air Pollutants

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1. Nielsen GD, Hansen JS, Lund RM, Bergqvist M, Larsen ST, Clausen SK, Thygesen P, Poulsen OM. IgE-mediated asthma and rhinitis I: a role of allergen exposure? Pharmacol Toxicol. 2002. 90:231–242.
2. Oh JW. Development of pollen concentration prediction models. J Korean Med Assoc. 2009. 52:579–591.
3. Jeon B, Lee J, Kim JH, Kim JW, Lee HS, Lee KH. Atopy and sensitization rates to aeroallergens in children and teenagers in Jeju, Korea. Korean J Asthma Allergy Clin Immunol. 2010. 30:14–20.
4. Spieksma FT, Emberlin JC, Hjelmroos M, Jager S, Leuschner RM. Atmospheric birch (Betula) pollen in Europe: trends and fluctuations in annual quantities and the starting dates of the seasons. Grana. 1995. 34:51–57.
5. Teranishi H, Kenda Y, Katoh T, Kasuya M, Oura E, Taira H. Possible role of climate change in the pollen scatter of Japanese cedar Cryptomeria japonica in Japan. Clim Res. 2000. 14:65–70.
6. Freye HB, King J, Litwin CM. Variations of pollen and mold concentrations in 1998 during the strong El Nino event of 1997-1998 and their impact on clinical exacerbations of allergic rhinitis, asthma, and sinusitis. Allergy Asthma Proc. 2001. 22:239–247.
7. Ziska LH, Gebhard DE, Frenz DA, Faulkner S, Singer BD, Straka JG. Cities as harbingers of climate change: common ragweed, urbanization, and public health. J Allergy Clin Immunol. 2003. 111:290–295.
8. Wan S, Yuan T, Bowdish S, Wallace L, Russell SD, Luo Y. Response of an allergenic species, Ambrosia psilostachya (Asteraceae), to experimental warming and clipping: implications for public health. Am J Bot. 2002. 89:1843–1846.
9. Ziska LH, Caulfield F. Rising CO2 and pollen production of common ragweed (Ambrosia artemisiifolia), a known allergy-inducing species: implications for public health. Aust J Plant Physiol. 2000. 27:893–898.
10. Wayne P, Foster S, Connolly J, Bazzaz F, Epstein P. Production of allergenic pollen by ragweed (Ambrosia artemisiifolia L.) is increased in CO2-enriched atmospheres. Ann Allergy Asthma Immunol. 2002. 88:279–282.
11. Rogers CA, Wayne PM, Macklin EA, Muilenberg ML, Wagner CJ, Epstein PR, Bazzaz FA. Interaction of the onset of spring and elevated atmospheric CO2 on ragweed (Ambrosia artemisiifolia L.) pollen production. Environ Health Perspect. 2006. 114:865–869.
12. Emberlin J, Mullins J, Corden J, Millington W, Brooke M, Savage M, Jones S. The trend to earlier birch pollen seasons in the U.K.: a biotic response to changes in weather conditions? Grana. 1997. 36:29–33.
13. Emberlin J, Detandt M, Gehrig R, Jaeger S, Nolard N, Rantio-Lehtimaki A. Responses in the start of Betula (birch) pollen seasons to recent changes in spring temperatures across Europe. Int J Biometeorol. 2002. 46:159–170.
14. Frenguelli G. Interactions between climatic changes and allergenic plants. Monaldi Arch Chest Dis. 2002. 57:141–143.
15. D'Amato G, Liccardi G, D'Amato M, Cazzola M. Outdoor air pollution, climatic changes and allergic bronchial asthma. Eur Respir J. 2002. 20:763–776.
16. Huynen M, Menne B. Phenology and human health: allergic disorders. Report of a WHO meeting, Rome, Italy, 16-17 January 2003. Health and global environmental change, series no. 1. 2003. Copenhagen: World Health Organization Regional Office for Europe.
17. Last J, Guidotti TL. Implications for human health of global ecological changes. Public Health Rev. 1990. 18:49–67.
18. Emberlin J. The effects of patterns in climate and pollen abundance on allergy. Allergy. 1994. 49:18 Suppl. 15–20.
19. Fischlin A, Midgley GF, Price JT, Leemans R, Gopal B, Turley C, Rounsevell MD, Dube OP, Tarazona J, Velichko AA. Parry M, Canziani O, Palutikof J, van der Linden P, Hanson C, editors. Ecosy-stems, their properties, goods and services. Climate change 2007: impacts, adaptation and vulnerability. Working group II contribution to the fourth assessment: report of the Intergovernmental Panel on Climate Change. 2007. Cambridge: Cambridge University Press;211–272.
20. Husar RB, Tratt DM, Schichtel BA, Falke SR, Li F, Jaffe D, Gasso S, Gill T, Laulainen NS, Lu F, Reheis MC, Chun Y, Westphal D, Holben BN, Gueymard C, McKendry I, Kuring N, Feldman GC, McClain C, Frouin RJ, Merrill J, DuBois D, Vignola F, Murayama T, Nickovic S, Wilson WE, Sassen K, Sugimoto N, Malm WC. Asian dust events of April 1998. J Geophys Res. 2001. 106:18317–18330.
21. Belmonte J, Alarcon M, Avila A, Scialabba E, Pino D. Long-range transport of beech (Fagus sylvatica L.) pollen to Catalonia (north-eastern Spain). Int J Biometeorol. 2008. 52:675–687.
22. Asero R. Birch and ragweed pollinosis north of Milan: a model to investigate the effects of exposure to "new" airborne allergens. Allergy. 2002. 57:1063–1066.
23. Hjelmroos M, Schumacher MJ, Van Hage-Hamsten M. Heterogeneity of pollen proteins within individual Betula pendula trees. Int Arch Allergy Immunol. 1995. 108:368–376.
24. Ahlholm JU, Helander ML, Savolainen J. Genetic and environmental factors affecting the allergenicity of birch (Betula pubescens ssp. czerepanovii [Orl.] Hamet-ahti) pollen. Clin Exp Allergy. 1998. 28:1384–1388.
25. Singer BD, Ziska LH, Frenz DA, Gebhard DE, Straka JG. Increasing Amb a 1 content in common ragweed (Ambrosia artemisiifolia) pollen as a function of rising atmospheric CO2 concentration. Funct Plant Biol. 2005. 32:667–670.
26. D'Amato G, Liccardi G, Frenguelli G. Thunderstorm-asthma and pollen allergy. Allergy. 2007. 62:11–16.
27. Katial RK, Zhang Y, Jones RH, Dyer PD. Atmospheric mold spore counts in relation to meteorological parameters. Int J Biometeorol. 1997. 41:17–22.
28. Pulimood TB, Corden JM, Bryden C, Sharples L, Nasser SM. Epidemic asthma and the role of the fungal mold Alternaria alternata. J Allergy Clin Immunol. 2007. 120:610–617.
29. Centers for Disease Control and Prevention (CDC). Health concerns associated with mold in water-damaged homes after Hurricanes Katrina and Rita: New Orleans area, Louisiana, October 2005. MMWR Morb Mortal Wkly Rep. 2006. 55:41–44.
30. Park SW. Effect of air pollution on acute exacerbation of adult asthma in Seoul, Korea. Korean J Med. 2010. 78:447–449.
31. Rossi OV, Kinnula VL, Tienari J, Huhti E. Association of severe asthma attacks with weather, pollen, and air pollutants. Thorax. 1993. 48:244–248.
32. D'Amato G. Outdoor air pollution, climate and allergic respiratory diseases: evidence of a link. Clin Exp Allergy. 2002. 32:1391–1393.
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