J Korean Neurosurg Soc.  2003 May;33(5):501-504.

Chordoid Glioma in the Third Ventricle: Case Report

• Koh EJ
• Choi HY

Abstract

Chordoid glioma of the central nervous system is a recently recognized tumor. It is necessary to be differentiated with the craniopharyngioma or other suprasellar masses due to its clinical and radiologic similarities. The authors report a patient of 47-year-old man with a chordoid glioma in the third ventricle who underwent total removal of the tumor. Preoperatively, the patient showed hypersomnia, memory disturbance, bitemporal hemianopsia, drowsy mental status, and striking weight gain(25Kg) during the last 5-6 months. MRI showed huge homogeneous enhancing mass(5x5x6cm), locating in the sellae extending to the third ventricle and corpus callosum. Tumor was removed via interhemispheric transcallosal interforniceal approach. Histopathologic finding was chordoid astrocytoma characteristically showing GFAP(+), EMA(-), Collagen type IV(-), ki-67(-), p53(-) in immunohistochemical stain and epithelioid cells with eosinophilic cytoplasm, mucinous matrix, high cellularity, no mitosis in H & E stain. Postoperatively, a patient recovered normal mental status, sleep pattern, and vision. Postoperative fractionated radiation therapy was done.

Keyword

Chordoid glioma; Third ventricle; Hypothalamus; Suprasellar region

MeSH Terms

Astrocytoma
Central Nervous System
Collagen
Corpus Callosum
Craniopharyngioma
Cytoplasm
Disorders of Excessive Somnolence
Eosinophils
Epithelioid Cells
Glioma*
Hemianopsia
Humans
Hypothalamus
Magnetic Resonance Imaging
Memory
Middle Aged
Mitosis
Mucins
Strikes, Employee
Third Ventricle*
Collagen
Mucins