J Korean Orthop Assoc.  2012 Dec;47(6):403-409. 10.4055/jkoa.2012.47.6.403.

Incidence and Prevention of Venous Thromboembolism in Severely Injured Patients with Lower Extremity Fracture

Affiliations
  • 1Department of Orthopaedic Surgery, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea. jjkim2@amc.seoul.kr
  • 2Department of Orthopaedic Surgery, Haeundae Paik Hospital, College of Medicine, Inje University, Busan, Korea.

Abstract

PURPOSE
To compare the incidence of venous thromboembolism (VTE) in severely injured patients with lower extremity fracture in a prophylactic group with that in a non-prophylactic group during a retrospective study.
MATERIALS AND METHODS
Severely injured patients with lower extremity fracture were enrolled in this study and were divided into the following two groups: Group I, non-prophylactic group, and Group II, prophylactic group using anticoagulants and mechanical prophylaxis.
RESULTS
Symptomatic VTE occurred in 5 cases (16.1%) among the 31 cases in Group I; i.e., deep vein thrombosis in one case and pulmonary embolism (PE) in four cases, including life threatening PE 2 cases. There were no patients with symptomatic VTE among the 32 cases in Group II.
CONCLUSION
The incidence of symptomatic VTE without the use of prophylaxis was 16.1%. This rate dramatically decreased with the use of prophylaxis. Therefore, we believe that prophylaxis with anticoagulants and mechanical device is necessary in order to prevent VTE in severely injured patients with lower extremity fracture.

Keyword

severely injured trauma patients; lower extremity fracture; venous thromboembolism; deep vein thrombosis; pulmonary embolism
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