J Korean Acad Rehabil Med.  2002 Jun;26(3):347-351.

Cerebral Infarct Caused by Ovarian Hyperstimulation Syndrome after Using an Ovulation Induction Agent: A case report

• Kim MO
• Jung HY
• Kim CH
• Kim SY

Abstract

Ovarian hyperstimulation syndrome (OHSS) is a serious complication of ovulation induction agents used for patients with ovulatory dysfunction. It's pathogenesis is uncertain, although increased capillary permeability with extravasation offluid into the abdominal cavity is most likely suggested. Early features of the syndrome include nausea, vomiting,diarrhea, ascites, pleural effusion, and ovarian enlargement. In severe cases, increased viscosity with hemoconcentration hypovolemia, oliguria, coagulopathy, and thromboembolism may appear, and eventually develop to cerebral infarct. We experienced a case of cerebral infarct caused by OHSS with antiphospholipid antibody syndrome after using an ovulation induction agent, and we present this rare case with the review of literature.

Keyword

Ovarian hyperstimulation syndrome; Antiphospholipid antibody syndrome; Cerebral infarct

MeSH Terms

Abdominal Cavity
Antiphospholipid Syndrome
Ascites
Capillary Permeability
Female
Humans
Hypovolemia
Nausea
Oliguria
Ovarian Hyperstimulation Syndrome*
Ovulation Induction*
Ovulation*
Pleural Effusion
Thromboembolism
Viscosity