J Korean Acad Rehabil Med.  2005 Dec;29(6):678-680.

Subacute Combined Degeneration of the Spinal Cord in Association with Pernicious Anemia: A case report

Affiliations
  • 1Department of Physical Medicine and Rehabilitation, Sun General Hospital, Korea. kjdmss11@naver.com

Abstract

Subacute combined degeneration is a disease of spinal cord involving the posterior and lateral columns due to vitamin B12 deficiency. We experienced a 56-year-old man suffering subacute combined degeneration, characterised by dysesthesia and disturbance of deep sensation such as position sense, proprioception and vibration sense in the lower extremities, and ataxic gait. We reported one patient with subacute combined degeneration of the cord in association with pernicious anemia resulting from inactivation of intrinsic factor by it's antibodies.

Keyword

Subacute combined degeneration; Pernicious anemia
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