Ann Dermatol.  2009 Feb;21(1):63-65. 10.5021/ad.2009.21.1.63.

A Case of Giant Folliculosebaceous Cystic Hamartoma

• Haw S
• Lee MH

• KMID: 2172070
• DOI: http://doi.org/10.5021/ad.2009.21.1.63

Abstract

Clinically, folliculosebaceous cystic hamartoma (FSCH) lacks distinct features, but it has been reported as an asymptomatic, 1- to 3-cm, dome-shaped nodule on the face. Histopathologically, FSCH is characterized by adnexal and folliculosebaceous cystic proliferation with various mesenchymal changes. This case presented an unusually large, small-fist-sized mass in the right mandibular area that was accompanied by intermittent itching. Histopathologic findings demonstrated appropriate features of FSCH. We present an interesting case of giant FSCH in a 48-year-old female.

Keyword

Folliculosebaceous cystic hamartoma; Giant

MeSH Terms

Female
Hamartoma
Humans
Middle Aged
Pruritus

Figure

• 

  Fig. 1 (A) The skin lesion is a skin-colored, cerebriform mass, 10.0×8.0×5.0 cm, in the right mandibular area. (B) The smooth surface has scattered, dilated hair follicle-like pores with a waxy discharge.

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  Fig. 2 (A) Numerous mature sebaceous lobules surround the cystic structures. There is some increase of muscle components on the left lower quadrant (H&E, ×40). (B) Increased numbers of small venules are shown around the fibroepithelial units (H&E, ×100).

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  Fig. 3 (A) A slight increase of smooth muscles is shown around fibroepithelial units (SMA, ×40). (B) Increased numbers of small venules are shown around fibroepithelial units. Some of these vessels are congested with red blood cells (CD31, ×40).

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