Ann Dermatol.  2016 Jun;28(3):400-401. 10.5021/ad.2016.28.3.400.

Blue Toe Syndrome as an Early Sign of Disseminated Intravascular Coagulation

Affiliations
  • 1Department of Dermatology, VHS Medical Center, Seoul, Korea. choikohy@gmail.com

Abstract

No abstract available.


MeSH Terms

Blue Toe Syndrome*
Disseminated Intravascular Coagulation*

Figure

  • Fig. 1 Blue to purple discoloration with petechiae on the right foot.

  • Fig. 2 (A) Scanning view (H&E, ×40). (B) Ischemic necrosis of epidermis, and red blood cell extravasation (H&E, ×200). (C) Eosinophilic fibrinoid thrombi in medium-sized vessels (arrow) and leukocytoslasis (H&E, ×400).


Reference

1. Chadachan V, Dean SM, Eberhardt RT. Cutaneous changes in peripheral arterial vascular disease. In : Goldsmith LA, Katz SI, Gilchrest BA, Paller AS, Leffell DJ, Wolff K, editors. Fitzpatrick's dermatology in general medicine. 8th ed. New York: McGraw Hill;2012. p. 2094–2110.
2. Hirschmann JV, Raugi GJ. Blue (or purple) toe syndrome. J Am Acad Dermatol. 2009; 60:1–20.
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3. Tschetter AJ, Liu V, Wanat KA. Cutaneous polyarteritis nodosa presenting as a solitary blue toe. J Am Acad Dermatol. 2014; 71:e95–e97.
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4. Thornsberry LA, LoSicco KI, English JC 3rd. The skin and hypercoagulable states. J Am Acad Dermatol. 2013; 69:450–462.
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5. Davis MP, Byrd J, Lior T, Rooke TW. Symmetrical peripheral gangrene due to disseminated intravascular coagulation. Arch Dermatol. 2001; 137:139–140.
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