Korean J Med.  2016 May;90(5):440-443. 10.3904/kjm.2016.90.5.440.

Development of a Complete Atrioventricular Block Associated with Intake of Evening Primrose Oil

  • 1Department of Internal Medicine, Sung Ae Hospital, Seoul, Korea. nkbk99@gmail.com
  • 2Department of Internal Medicine, Gwangmyeong Sung Ae Hospital, Gwangmyeong, Korea.


A complete atrioventricular block is seen in patients due to a variety of causes, including drugs. The resolution of a drug-induced atrioventricular block is often accomplished by drug discontinuation. We report a case of a complete atrioventricular block in a 31-year-old woman following a month of treatment with evening primrose oils. After excluding all other likely causes of conduction disorders, an adverse effect of the evening primrose oils seemed to be the most likely diagnosis. After discontinuation of the oils, no associated symptoms or conduction disturbances were observed for 4 months after discharge. We stress the reconsideration of taking medicines and functional foods continuously as most patients are not aware of the hazards they pose.


Atrioventricular block; Evening primrose oil
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