Yonsei Med J.  2013 Jul;54(4):1049-1052. 10.3349/ymj.2013.54.4.1049.

Crown-Rump Length Measured in the Early First Trimester as a Predictor of Low Birth Weight

• Kang JY
• Park EJ
• Yang YS
• Park M
• Park WI

• KMID: 2158244
• DOI: http://doi.org/10.3349/ymj.2013.54.4.1049

Abstract

The aim of this study is to assess the association between crown-rump length (CRL) measured before the 10th gestational week and birth weight. Results from 316 transvaginal ultrasonography scans at the 46th, 53rd, 60th, 67th, and 74th days of pregnancy were compared in low birth weight (LBW) versus normal birth weight groups. A positive correlation between CRL and birth weight was observed when CRL was measured at days 60, 67, and 74. CRL measured on the 67th day of pregnancy was significantly smaller in the LBW group than in the normal birth weight group. A cut-off value of CRL=26.5 mm measured at day 67 has the highest power to predict LBW.

Keyword

Crown-rump length; low birth weight; ultrasonography

MeSH Terms

Adult
*Crown-Rump Length
Female
Fertilization in Vitro
Gestational Age
Humans
*Infant, Low Birth Weight
Infant, Newborn
Maternal Age
Predictive Value of Tests
Pregnancy
*Pregnancy Trimester, First
Ultrasonography, Prenatal
Young Adult

Figure

• 

  Fig. 1 ROC curve for prediction of low birth weight (<2500 g) for each ultrasonography date. Gestational days 60, 67 and 74 have larger areas under the curve than other days. ROC, receiver operating characteristic.

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