J Korean Med Sci.  2002 Feb;17(1):49-52. 10.3346/jkms.2002.17.1.49.

Cleft lip and Palate Incidence Among the Live Births in the Republic of Korea

  • 1Department of Reconstructive Plastic Surgery, College of Medicine, Seoul National University, Seoul, Korea. kimsw@snu.ac.kr
  • 2Division of Pediatric Plastic Surgery, Seoul National University Children's Hospital, Seoul, Korea.
  • 3Ye Plastic & Aesthetic Surgery Clinic, Seoul, Korea.


We present an epidemiologic study of cleft lip and palate in the Republic of Korea from January 1, 1993 through December 31, 1993. In 1993, the number of total live births was 715,817. And from 1993 through 1995, a total of 1,293 new patients with cleft lip and palate who were born in 1993 were identified. The incidence of cleft lip and palate was 1.81 per 1000, that is, 1 per 554 live births. The cleft lip: cleft lip and palate: cleft palate alone ratio was 1.13:1:1.19. The male: female ratio was 2.1:1 in the cleft lip group, and 2.5:1 in the cleft lip and palate group. We could detect a male predominance in both groups. In contrast, the ratio was 0.95:1 in the cleft palate group. The left: right: bilateral ratio was 1.9:1:0.23 in cleft lip group, and the ratio was 2.2:1:1.1 in the cleft lip and palate group. This is the first nation-wide study to provide detailed data on the incidence of cleft lip and palate in the live births in the Republic of Korea.


Cleft Lip; Cleft Palate; Incidence; Korea; Epidemiology

MeSH Terms

Cleft Lip/*epidemiology
Cleft Palate/*epidemiology
Infant, Newborn

Cited by  2 articles

Characteristics of MSX1 gene in Korean nonsyndromic cleft lip and palate individuals
Hae-Kyung Lee, Seong-Sik Kim, Woo-Sung Son
Korean J Orthod. 2008;38(2):133-143.    doi: 10.4041/kjod.2008.38.2.133.

Trend of health care utilization of cleft lip and/or palate in Korea during 2007–2016
Mihee Hong, Seung-Hak Baek
Korean J Orthod. 2018;48(4):216-223.    doi: 10.4041/kjod.2018.48.4.216.

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