J Pathol Transl Med.  2015 Jul;49(4):346-350. 10.4132/jptm.2015.04.17.

Necrotizing Sarcoid Granulomatosis: Possibly Veiled Disease in Endemic Area of Mycobacterial Infection

• Chong Y
• Lee EJ
• Kang CS
• Kim TJ
• Song JS
• Shim H

• KMID: 2151147
• DOI: http://doi.org/10.4132/jptm.2015.04.17

Abstract

No abstract available.

Figure

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  Fig. 1. Radiologic findings. (A, B) Computed tomography (CT) of case 1 shows multiple variably-sized nodular lesions with hilar node enlargement. (C) Follow-up CT after one month of corticosteroid therapy reveals dramatic resolution. (D) CT of case 2 also reveals multiple ill-defined nodules.

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  Fig. 2. Microscopic findings. (A–C) Multifocal nodular granulomatous inflammation with extensive central necrosis is replacing normal architecture (case 1). (D) Mild transmural vasculitis distant from necrotic area, i.e., cicatricial-type vasculitis, is observed. (E, F) Multiple confluent granulomas with central caseous necrosis and granulomatous vasculitis are found (case 2).

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