J Korean Ophthalmol Soc.  1998 Jul;39(7):1446-1452.

Analysis of Foveal Hemodynamics between Normal and Stage I Macular Hole with Scanning Laser Doppler Flowmetry (HRF:Heidelberg Retinal Flowmetry)

Affiliations
  • 1The Institute of Vision Research, College of Medicine, Yonsei University, Seoul, Korea.
  • 2Department of Ophthalmology, College of Medicine, Yonsei University, Seoul, Korea.

Abstract

The exact pathophysiology of stage I macular hole has been unknown. But several factors have been found that have a potentials to develop and progress of macular hole. The hemodynamic changes on macular hole was one of them and the purpose of this study was to evaluate the hemodynamic differences between the normal and the stage I macular hole. Blood volume, flow and velocity on fovea and parafoveal area were measured with Heidelberg Retinal Flowmetry(HRF, Heidelberg Engineering, W. Germany). After the evaluation, the blood flow was significantly decreased on the foea in Stage I macular hole patients (P<0.001). These findings suggest that stage I macular hole maybe induced by decreased flood flow. And HRF has a potential for a new measuring modality of hemodynamics for mcular disease suggest.

Keyword

Blood flow; HRF; Stage I macular hole

MeSH Terms

Blood Volume
Hemodynamics*
Humans
Laser-Doppler Flowmetry*
Retinal Perforations*
Retinaldehyde*
Retinaldehyde
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