Korean J Dermatol.  1986 Apr;24(2):238-241.

Treatment of Recalcitrant Rosacea with 13 - Cis - Retinoic Acid

• Hur H
• Whang KU
• Lee CW
• Kim JH
• Kim JH

Abstract

Eight men with a one-ta-seven-year history of rosacea which poorly controlled by oral tetracycline or metronidazole, with or without topical medications, were given 13-cis-retinoic acid in dosages of p.5 to 0. 7 mg/kg/day for eight weeks. The size of erytherna and the number of papules had been gradually decreased since the second week of treatment. Eight weeks later more than 75p, regression was recognized in six patients, however telangiectasia remained unchanged. All eight patients complained of only mild degrees of cheilitis and dryness of the nose, and had no evidence of the serologic abnormalities on the tests examined during the period of therapy.

Keyword

Recalcitrant rosacea; 13 - Cis - retinoic acid

MeSH Terms

Cheilitis
Humans
Isotretinoin
Male
Metronidazole
Nose
Rosacea*
Telangiectasis
Tetracycline
Tretinoin*
Isotretinoin
Metronidazole
Tetracycline
Tretinoin