J Korean Surg Soc.
2002 Oct;63(4):345-349.
Nonfunctioning Huge Malignant Pheochromocytoma with Liver Metastasis
- Affiliations
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- 1Department Surgery, College of Medicine, Hanyang University, Seoul, Korea. leeks@hanyang.ac.kr
- 2Department Pathology, College of Medicine, Hanyang University, Seoul, Korea.
Abstract
- A 27-year-old woman with a 4-month history of right upper quadrant dull pain and normal blood pressure was admitted in May 2001. Abdominal ultrasonography and abdominal computed tomography revealed a huge retroperitoneal mass with hepatic nodules. Histologic diagnosis was paraganglioma based on gun biopsy. Hormonal study for pheochromocytoma was negative. I-metaiodobenzylguanidine (MIBG) scintigraphy and angiography were performed for operation. The tumor was removed en bloc with part of the pancreas, spleen and hepatic mass. Pathologic examination with immunohistochemical staining revealed a malignant pheochromocytoma growing exophytically from the left adrenal and metastasizing to the liver. The postoperative course has been uneventful and no recurrence has been noted over a 2-months follow-up period.
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