J Korean Soc Biol Psychiatry.  2001 Jun;8(1):162-166.

Three Cases of Mirtazapine Induced Akathisia

• Lee SH
• Nam M
• Chung YC

Abstract

The mirtazapine is a relatively new antidepressant that has noradrenergic and specific serotonin antagonist action(NaSSAs). This has been known as one of the most safest drugs because of its few side effects. Until now, there have been only one case report that mirtazapine causes a EPS side effect(restless leg syndrome). But the peculiar mechanism of this drug makes it impossible to explain the exact reasons why the mirtazapine could induce EPS symptoms. Authors obseved three cases of mirtazapine indeced akathisia. We could not explain the phenomenon the other way except akathisia. So here we presents the three case of mirtazapine induced akathisia and a few possible hypothesis of this phenomenon.

MeSH Terms

Leg
Psychomotor Agitation*
Serotonin
Serotonin