Korean J Urol.  2007 Feb;48(2):226-229. 10.4111/kju.2007.48.2.226.

Leydig Cell Tumor in Cryptorchid Testis

• Kim BS
• Sung WS
• Kim YS
• Yoon GS
• Kim HT
• Yoo ES

• KMID: 2139765
• DOI: http://doi.org/10.4111/kju.2007.48.2.226

Abstract

Leydig cell tumors are rare, constituting only 1-3% of all testicular tumors; but they are still the focus of interest due to the difficulties in determining their exact nature and subsequent type of treatment. Generally, there appears to be no association with cryptorchidism, but there have been reports of Leydig cell tumors in cryptorchid testes. Herein, a case of a Leydig cell tumor in cryptorchidism is reported.

Keyword

Leydig cell tumor; Cryptorchidism

MeSH Terms

Cryptorchidism
Leydig Cell Tumor*
Male
Testicular Neoplasms
Testis*

Figure

• 

  Fig. 1 An abdominal-pelvic computed tomography (CT) scan shows an approximately 9.2×7.3cm sized homogeneous mass lesion in the left inguinal canal. Multiple tiny calcifications and a small low density area can be observed, suspicious of necrosis.

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  Fig. 2 The cross section of the gross finding shows a yellowish round, solid mass.

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  Fig. 3 Histological features of the Leydig cell tumor of the testis. (A) Large polygonal cells, with abundant eosinophilic cytoplasm and crystaloid of Reinke in the interstitium (B) pronounced nuclear and cellular pleomorphism (H&E, ×400).

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  Fig. 4 Immunohistochemistry showing positive staining for α-inhibin (A: Inhibin, ×200) and negative staining for cytokeratin (B: CK, ×200).

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