J Korean Med Assoc.  2007 Feb;50(2):127-133. 10.5124/jkma.2007.50.2.127.

Assessment of Coronary Artery Bypass Graft Patency Using Multidetector Computed Tomography

Affiliations
  • 1Department of Radiology, University of Ulsan College of Medicine, Korea. seojb@amc.seoul.kr

Abstract

Coronary artery bypass graft surgery (CABG) is the standard of care in the treatment of advanced coronary artery disease. Invasive coronary angiography has been used to assess the status of graft. Recently, multidetector computed tomography (MDCT) has emerged as an important diagnostic tool for the evaluation of graft patency. Many studies have shown that MDCT has a high sensitivity and specificity in detecting graft occlusion or high-grade stenosis. However, there are several diagnostic pitfalls in evaluating CABG graft patency due to several factors, including technical factors, patient factors, and flow competition. Acknowledgment of these pitfalls and remedies to avoid wrong interpretation is essential to improve diagnostic accuracy. In addition, MDCT yields additional information such as plural effusion, pericardial effusion, sternal infection, pneumonia, pulmonary embolism, and so on. The continuing advance in the MDCT technology suggests that MDCT will be a rapid, convenient, and noninvasive tool in evaluating CABG patients in the near future.

Keyword

Computed tomography; Coronary artery disease; Coronary artery bypass graft

MeSH Terms

Constriction, Pathologic
Coronary Angiography
Coronary Artery Bypass*
Coronary Artery Disease
Coronary Vessels*
Humans
Multidetector Computed Tomography*
Pericardial Effusion
Pneumonia
Pulmonary Embolism
Sensitivity and Specificity
Standard of Care
Transplants

Figure

  • Figure 1 Patent internal mammary artery graft anastomosed to left anterior descending artery. Coronal image and volume rendered image (A and B) show the patent, contrast-filled internal mammary artery (arrows), which is well correlated with conventional angiogram (C)

  • Figure 2 Variable coronary artery bypass grafts. Patent saphenous vein graft from ascending aorta, anastomosed to distal right coronary artery (arrow) is shown in both volume rendered MDCT (A) and conventional angiogram (B). Patent radial artery graft to an obtuse marginal branch is also visualized on both images (C and D). The left internal mammary artery graft to left anterior descending artery is not visualized on MDCT images (A and C). Insteads, multiple surgical clips around left anterior descending artery are shown as nodular lesions (arrowhead in C). Catheter angiogram confirmed the graft failure (not shown)

  • Figure 3 Patent right gastroepiploic artery graft anastomosed to posterior descending artery. Both volume rendered MDCT image (A) and conventional angiogram (B) show patent graft

  • Figure 4 A saphenous graft stenosis. Volume rendered MDCT images (A) shows vocal narrowing of distal portion of saphenous vein graft (arrow), which is confirmed at conventional angiogram (arrow in B)

  • Figure 5 Saphenous vein graft occlusion in immediate postoperative period due to acute thrombosis. MDCT image shows saphenous vein graft filled with thrombus with soft tissue density (arrows)

  • Figure 6 False negative interpretation due to surgical clip at anastomosis site. Oblique MDCT image (A) shows good opacification of left internal mammary artery graft (arrow) anastomosed to left anterior descending artery. Metallic surgical clips (arrowhead) hamper the detailed evaluation of anastomosis site. Catheter angiogram (B) shows focal stenosis, resulting in false negative interpretation of MDCT

  • Figure 7 Vasospasm of graft mimicking significant stenosis. Volume rendered MDCT image (A) obtained 5 days after CABG shows multifocal areas of luminal narrowing at radial artery graft (arrows). MDCT image (B) obtained 6 months later shows patent graft, confirming the vasospasm at early postoperative period


Reference

1. Bourassa MG, Fisher LD, Campeau L, Gillespie MJ, Mc-Conney M, Lesperance J. Long-term fate of bypass grafts: the coronary artery surgery study (CASS) and Montreal Heart Institute experiences. Circulation. 1985. 72:V71–V78.
2. Aruny JE. Baum S, editor. Complications of coronary arteriography. Abrams' angiography: vascular and interventional radiology. 1997. 4th ed. Boston: Little, Brown and Company;572–582.
3. de Bono DP, Samani NJ, Spyt TJ, Hartshorne T, Thrush AJ, Evans DH. Transcutaneous ultrasound measurement of blood-flow in internal mammary artery to coronary artery grafts. Lancet. 1992. 339:379–381.
Article
4. Gomes AS, Lois JF, Drinkwater DC Jr, Corday SR. Coronary artery bypass grafts: visualization with MR imaging. Radiology. 1987. 162:175–179.
Article
5. Langerak SE, Vliegen HW, de Roos A, Zwinderman AH, Jukema JW, Kunz P, Lamb HJ, van Der Wall EE. Detection of vein graft disease using high-resolution magnetic resonance angiography. Circulation. 2002. 105:328–333.
Article
6. Ha JW, Cho SY, Shim WH, Chung N, Jang Y, Lee HM, Choe KO, Chung WJ, Choi SH, Yoo KJ, Kang MS. Noninvasive evaluation of coronary artery bypass graft patency using three-dimensional angiography obtained with contrast-enhanced electron beam CT. Am J Roentgenol. 1999. 172:1055–1059.
Article
7. Achenbach S, Moshage W, Ropers D, Nossen J, Bachmann K. Noninvasive, three-dimensional visualization of coronary artery bypass grafts by electron beam tomography. Am J Cardiol. 1997. 79:856–861.
Article
8. Ueyama K, Ohashi H, Tsutsumi Y, Kawai T, Ueda T, Ohnaka M. Evaluation of coronary artery bypass grafts using helical scan computed tomography. Catheter Cardiovasc Interv. 1999. 46:322–326.
Article
9. Hong C, Becker CR, Huber A, Schoepf UJ, Ohnesorge B, Knez A, Bruning R, Reiser MF. ECG-gated reconstructed multi-detector row CT coronary angiography: effect of varying trigger delay on image quality. Radiology. 2001. 220:712–717.
Article
10. Kim HJ, Seo JB, Lee YK, Do KH, Heo JN, et al. ECG-gated CT angiography for the assessment of coronary bypass graft patency: the influence of heart rate, type of bypass graft, target vessel and surgical technique on the diagnostic accuracy. J Korean Radiol Soc. 2006. 54:11–17.
Article
11. Ropers D, Ulzheimer S, Wenkel E, Baum U, Giesler T, Derlien H, Moshage W, Bautz WA, Daniel WG, Kalender WA, Achenbach S. Investigation of aortocoronary artery bypass grafts by multislice spiral computed tomography with electrocardiographic-gated image reconstruction. Am J Cardiol. 2001. 88:792–795.
Article
12. Nieman K, Pattynama PMT, Rensing BJ, van Geuns R-JM, de Feyter PJ. Evaluation of patients after coronary artery bypass surgery: CT angiographic assessment of grafts and coronary arteries. Radiology. 2003. 229:749–756.
Article
13. Marano R, Storto ML, Maddestra N, Bonomo L. Non-invasive assessment of coronary artery bypass graft with retrospectively ECG-gated four-row multi-detector spiral computed tomography. Eur Radiol. 2004. 14:1353–1362.
Article
14. Schlosser T, Konorza T, Hunold P, Kuhl H, Schmermund A, Barkhausen J. Noninvasive visualization of coronary artery bypass grafts using 16-detector row computed tomography. J Am Coll Cardiol. 2004. 44:1224–1229.
Article
15. Ropers D, Pohle FK, Kuettner A, Pflederer T, Anders K, Daniel WG, Bautz W, Baum U, Achenbach S. Diagnostic accuracy of noninvasive coronary angiography in patients after bypass surgery using 64-slice spiral computed tomography with 330-ms gantry rotation. Circulation. 2006. 114:2334–2341.
Article
16. Frazier AA, Qureshi F, Read KM, Gilkeson RC, Poston RS, White CS. Coronary artery bypass grafts: assessment with multidector CT in the early and late postoperative settings. RadioGraphics. 2005. 25:881–896.
Article
17. Rossi R, Chiurlia E, Ratti C, Ligabue G, Romagnoli R, Modena MG. Noninvasive assessment of coronary artery bypass graft patency by multislice computed tomography. Ital Heart J. 2004. 5:36–41.
Full Text Links
  • JKMA
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr