Yonsei Med J.  2014 Jul;55(4):1152-1156. 10.3349/ymj.2014.55.4.1152.

Hydrogen Peroxide as an Effective Disinfectant for Pasteurella multocida

• Jung IS
• Kim HJ
• Jung WY
• Kim CW

• KMID: 2130846
• DOI: http://doi.org/10.3349/ymj.2014.55.4.1152

Abstract

Pasteurella multocida (P. multocida) infections vary widely, from local infections resulting from animal bites and scratches to general infections. As of yet, no vaccine against P. multocida has been developed, and the most effective way to prevent pathogenic transmission is to clean the host environment using disinfectants. In this study, we identified which disinfectants most effectively inhibited environmental isolates of P. multocida. Three readily available disinfectants were compared: 3% hydrogen peroxide (HP), 70% isopropyl alcohol, and synthetic phenol. In suspension tests and zone inhibition tests, 3% HP was the most promising disinfectant against P. multocida.

Keyword

Pasteurella multocida; human pathogen; environmental isolate; disinfectant; 3% hydrogen peroxide

MeSH Terms

Disinfectants/*pharmacology
Hydrogen Peroxide/*pharmacology
Microbial Sensitivity Tests
Pasteurella multocida/*drug effects
Disinfectants
Hydrogen Peroxide

Figure

• 

  Fig. 1 Results of the zone inhibition test against Pasteurella multocida. The inhibition zone sizes for each disinfectant were measured with vernier calipers. *Significant difference vs. negative control (p<0.001). †The index of disinfectant strength was calculated as the ratio between the mean inhibition zone size (mm) for each disinfectant and that of hard water (negative control).

• 

  Fig. 2 Representative result of a zone inhibition test against Pasteurella multocida. a, hard water (negative control); b, synthetic phenol (0.07% 2-phenylphenol and 0.06% p-tertiary amylphenol); c, 70% isopropyl alcohol; d, 3% hydrogen peroxide.

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