Korean J Otorhinolaryngol-Head Neck Surg.
2015 Nov;58(11):781-785. 10.3342/kjorl-hns.2015.58.11.781.
Unexpected Bleeding Following Endoscopic Sinus Surgery Leading to the Rare Diagnosis of Acquired Haemophilia A
- Affiliations
-
- 1Department of Otorhinolaryngology-Head and Neck Surgery, Konkuk University School of Medicine, Seoul, Korea. entalk@kuh.ac.kr
- KMID: 2129809
- DOI: http://doi.org/10.3342/kjorl-hns.2015.58.11.781
Abstract
- We report a case of acquired hemophilia A following endoscopic sinus surgery. The patient was a 64-year-old man whose preoperative activated partial thromboplastin time (aPTT) was slightly prolonged. He underwent endoscopic sinus surgery for chronic rhinosinusitis with nasal polyp. Nasal bleeding occurred spontaneously on the postoperative day 3. The aPTT was prolonged at 58.9 s, with factor VIII activity of 21% and a positive factor VIII inhibitor. Treatment with factor VIII and methylprednisolone resulted in remission within 1 month. This is the first of such case reported in Korea; the patient was treated by recombinant factor VIII replacement and steroid therapy.
Keyword
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Identification of a shared F8 mutation in the Korean patients with acquired hemophilia A
- Endoscopic Diagnosis and Treatment of Isolated Sphenoid Sinus Lesions
- Acquired Hemophilia A with Gastrointestinal Bleeding
- A Case of the Carotid-Cavernous Fistula Due to the Internal Carotid Artery Injury During Endoscopic Sinus Surgery
- Esophageal Sinus Formation due to Cyanoacrylate Injection for Esophageal Variceal Ligation-induced Ulcer Bleeding in a Cirrhotic Patient
