J Korean Ophthalmol Soc.
2001 Aug;42(8):1139-1142.
Cyclosporin A in High Risk Penetrating Keratoplasty
- Affiliations
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- 1Department of Ophthalmology, Asan Medical Center, College of Medicine Ulsan University, Seoul, Korea.
Abstract
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PURPOSE: To conform the effectiveness of Cyclosporin(CsA) in penetrating keratoplasty(PKP), we compared the survival rate of grafts between CsA-used group and CsA-unused group(control group) in high risk patients.
MATERIAL AND METHOD: High risk cornea was defined as vascularization in 3 or 4 quadrants, recurrent graft or corneal surface disease. We reviewed the 74 eyes(74 patients) which received penetrating keratoplasty with high risk cornea, and compared the survival rate between CsA-used group and control group.
RESULT: Twenty-nine of the 74 patients were treated with CsA(17 patients with topical CsA and 12 with oral CsA ). The survival rate of CsA-used group was not superior to that of control group.
CONCLUSION
CsA seems not to be effective in graft survival of high risk PKP.
