J Korean Ophthalmol Soc.  1995 Nov;36(11):1870-1875.

The Comparison of the Effect of Therapeutic Lrens, Collagen Shield, and Tarsorrhaphy on Stromal Inflammation after Photorefractive Keratectomy in a Rabbit model

• Kim IS
• Kim HM
• Jung HR

Abstract

Reducing inflammation after photo refractive keratectomy may decrease postoperative pain and reduce corneal haze intensity. We evaluated the effect of the therapeutic lens(T-lens) and collagen shield on stromal inflammation. Adult New Zealand white rabbits were subjected to excimer laser PRK. Polymorphonuclear leukocytes(PMNs) of ablated corneal stroma were counted 10 hours after surgery with a microscope. The number of PMNs in the central cornea was lower in the T-lens group (29.77 +/- 11.6) and collagen shield group(36.77 +/- 5.9) than in the tarsorrhaphy group (75.33 +/- 14.6). Of all the groups, the eyes which were left unpatched showed the most marked infiltration of PMNs into the wound(226.83 +/- 18.2). The T-lens and collagen shield may reduce postoperative corneal haze intensity better than a pressure patch by suppression of stromal inflammation.

Keyword

Collagen shield; Photorefractive keratectomy; Tarsorrhaphy; Therapeutic lens

MeSH Terms

Adult
Collagen*
Cornea
Corneal Stroma
Humans
Inflammation*
Lasers, Excimer
Pain, Postoperative
Photorefractive Keratectomy*
Rabbits
Collagen