J Korean Ophthalmol Soc.  1980 Dec;21(4):563-567.

A Case of Vogt-Koyanagi-Harada Syndrome

• Huh K
• Cho DS
• Sohn MS

Abstract

Vogt-Koyanagi-Harada syndrome is characterized by bilateral uveitis, alopecia, poliosis, dysacousia, and sings of meningeal irritation. Vogt-Koyanagi syndrome is a severe anterior uveitis associated with alopecia, vitiligo, poliosis, and dysacousia. On the other hand, Harada's disease is primarily a posterior uveitis accompanied by sings of meningeal irritation and abnormalities of cerebrospinal fluid. The overlapping of clinical manifestations between two entities have justified as part of a spectrum of one disease. The etiology is not clearly determined but two most reliable theories as to the cause of the Vogt-Koyanagi-Harada syndrome have been considered as allergic reaction to the uveal pigment or viral infection. The authors experienced a 27-year-old Korean male who had acute bilateral uveitis, headache, dysacousia, alopecia, poliosis, vitiligo on the back, and retinal pigment epithelial detachment of posterior pole in the fluorescein angiography. Thus the authors present this case with clinical manifestations, fluorescein angiographic findings. our schedule of steroid therapy, and review of literatures.

MeSH Terms

Adult
Alopecia
Appointments and Schedules
Cerebrospinal Fluid
Fluorescein
Fluorescein Angiography
Hand
Headache
Humans
Hypersensitivity
Male
Retinal Detachment
Uveitis
Uveitis, Anterior
Uveitis, Posterior
Uveomeningoencephalitic Syndrome*
Vitiligo
Fluorescein