J Korean Ophthalmol Soc.  1995 Jan;36(1):103-108.

Pathologic Changes after Inferior Oblique Marginal Myotomy in Rabbits: The Effect of Triamcinolone

Affiliations
  • 1Department of Ophthalmology, Korea Veterans Hospital, Seoul, Korea.
  • 2Department of Ophthalmology, College of Medicine, Seoul National University, Seoul, Korea.

Abstract

In the margial myotomy of inferior oblique muscle(IO myotomy), only the overaction of the muscle is eliminated and the normal action of the inferior oblique saved. Steroid is usually used to prevent the adhesion of the tissue after IO myotomy, subconjunctivally. The myotomy of IO was performed in 14 white rabbits which were divided into two groups, one group having local injection of triamcinolone after IO myotomy and the other not having it. At postoperative 1 month, there were edema of the muscle fibers and infiltration of the inflammatory cells. Three months postoperatively, ingrowth of fibrous tissue and atrophy of the muscle fibers were found. Those changes were less prominent in the group with triamcinolone injection. This study revealed that subconjunctival triamcinolone injection after the IO marginal myotomy produce a good effect on the prevention of postoperative adhesion in the long term.

Keyword

Fibrous tissue infiltration; Histopathologic changes; Inferior oblique marginal myotomy; Inflammatory reactions; Triamcinolone

MeSH Terms

Atrophy
Edema
Rabbits*
Triamcinolone*
Triamcinolone
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