J Korean Orthop Assoc.
2002 Dec;37(6):810-813.
Gorham's Disease Involving the Shoulder Joint: A Case Report
- Affiliations
-
- 1Department of Orthopedic Surgery, College of Medicine, Dong-A University, Busan, Korea. Kimch@daunet.donga.ac.kr
- 2Department of Pathology, College of Medicine, Dong-A University, Busan, Korea.
Abstract
- Gorham's disease is a rare vanishing bone disease characterized by massive osteolysis and replacement with numerous wide engorged capillaries. The exact nature and effective treatment modalities for this condition are as yet unclear. A fifty-years old female, who had unexplained destruction of the left shoulder joint, was diagnosed as having Gorham's disease according to histopathological (capillary tissue aggregation) and immunopathological (immunoreactions with IL-1alpha and IL-6) studies. Although we treated her with antiresorptive medication and radiotherapy, which are current treatment modalities, the destructive process progressed. We report upon this case and provide a review of its literature.
