J Korean Soc Ther Radiol.  1997 Dec;15(4):287-296.

Clinical Application of 3-D Conformal Radiotherapy for Carcinoma of the Ethmoid Sinus: I. Comparative Analysis Between Conventional 2-D and 3-D Conformal Plans

• Lee S
• Kim GE
• Keum KC
• Park HC
• Cho JH
• Han SU
• Lee KK
• Suh CO
• Hong WP
• Park IY

Abstract

PURPOSE
This is study of whether 3-D conformal radiotherapy for carcinomas of the ethmoid sinus were better than those treated with conventional 2-D plan.
MATERIALS AND METHODS
The 3-D conformal treatment plans were compared with conventional 2-D plans in 4 patients with malignancy of the ethmoid sinus. Isodose distribution, dose statistics, and dose volume histogram of the planning target volume were used to evaluate differences between 2-D and 3-D plans. In addition, the risk of radiation exposure of surrounding normal critical organs are evaluated by means of point dose calculation and dose volume histogram.
RESULTS
: 3-D conformal treatment plans for each patient that the better tumor coverages by the planning target volume with improved dose homogeneity, compared to 2-D conventional treatment plans in the same patient. On the other hand, the radiation dose distributions to the surrounding normal tissue organs, such as the orbit and optic nerves are not significantly reduced with our technique, but a substantial sparing in the brain stem and optic chiasm for each patient.
CONCLUSION
: Our findings represented the potential advantage of 3-D treatment planning for dose homogeniety as well as sparing of the normal tissue surrounding the tumor. However, further investigational studies are required to define the clinical benefit.

Keyword

3-D conformal treatment; carcinoma of the ethmoid sinus

MeSH Terms

Brain Stem
Ethmoid Sinus*
Hand
Humans
Optic Chiasm
Optic Nerve
Orbit
Radiotherapy, Conformal*