Korean J Dermatol.  2001 Jul;39(7):794-797.

Contact Dermatitis due to Ketoprofen Patch(Ketotop(R))

• Yun NH
• You DO
• Lee SW
• Park SD
• Cha SH

Abstract

Ketoprofen is an nonsteroidal anti-inflammatory drug derived from propionic acid. It has been widely used as topical preparations, as gel or patch. It has been reported that topical ketoprofen can cause contact dermatitis and photocontact dermatitis. We experienced five cases of contact dermatitis, developed after applying ketoprofen patch(Ketotop(R), Pacific pharmaceutical Co., Korea) for the control of oste omuscular or joint pain. While one patient had generalized urticarial eruption, the rest of patents showed localized erythematous pruritic eczematous skin eruptions. It was verified through intradermal skin test and pin prick test that ketoprofen itself was not the causative drug for the skin eruption. Patch test excluded the possibility of allergic skin reaction to rubber compounds. It should be elucidated which compounds are allergic or toxic to the skin, contained in woven fabrics.

Keyword

Ketoprofen patch; Contact dermatitis

MeSH Terms

Arthralgia
Dermatitis, Contact*
Dermatitis, Photoallergic
Diethylpropion
Humans
Ketoprofen*
Patch Tests
Rubber
Skin
Skin Tests
Diethylpropion
Ketoprofen
Rubber