Korean J Dermatol.
1999 Feb;37(2):163-167.
Treatment with Low-Dose Danazol in Livedo Vasculitis
Abstract
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BACKGROUND: Several modalities have been used for the treatment of livedo vasculitis. However, in some cases conspicious morbidity is caused by recurrent painful ulceration resistant to therapy.
OBJECTIVE
This study was conducted to determine the effectiveness and adverse effects of the danazol in treatment of livedo vasculitis.
METHODS
Nine patients with ulcerative lesions due to livedo vasculitis were included for danazol therapy. Danazol 200mg was administered daily for 4 to 8 weeks.
RESULTS
Eight of the patients showed remarkable improvement and were satisfied with this therapy. Significant adverse effects were not observed.
CONCLUSION
We suggest that a low dose of danazol may be considered as the first line of treatment and is worthwhile to try in cases recalcitrant to the other treatment.
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