Korean J Dermatol.  1989 Dec;27(6):781-785.

A Case of Leser - Trelat Sign Associated with Small Cell Carcinoma of the Lung

• Chun TJ
• Kim MN
• Choi BW
• Song KY
• Ro BI
• Chang CY

Abstract

Leser-Trelat sign is characterized by the sudden appearance and rapid increase in number and size of seborrheic keratoses associated with an internal malignancy. A 78-year-old woman showed multiple pea to bean sized dark brownish papules and plsques on the trunk. Skin lesions had appeared suddenly since 5 months ago and then rapidly increased in number and size. The histopathologic exsmination of the skin lesions revealed seborrheic keratoses. The chest roentgenogram revealed the mass shadow on the right hilar region and transbronchial lung biopsy revealed small cell carcinoma.

Keyword

Leser-Trelat sign; Small cell carcinoma; Lung

MeSH Terms

Aged
Biopsy
Carcinoma, Small Cell*
Female
Humans
Keratosis, Seborrheic
Lung*
Peas
Skin
Thorax