Korean J Nephrol.  2000 Mar;19(2):358-362.

A Case of Microscopic Polyangiitis

• Lee MS
• Lee SK
• Lee JH
• Ahn SH
• Song JH

Abstract

Microscopic polyangiitis is a systemic small vessel vasculitis, which, although primarily associated with necrotizing and crescentic glomerulonephritis and pulmonary capillaritis, often has cutaneous and muscul-oskelectal features. Microscopic polyangiitis is strongly associated with antineutrophil cytoplamic autoantibody that are a useful diagnostic serologic marker for the most common form of necrotizing vasculitis, and that have two patterns(C-ANCA and P-ANCA). We have experienced a case of microscopic polyangiitis with purpurae on both lower extrimities, C-ANCA positive and cresent formation on renal biopsy, which had no history of asthma and no pathologic evidence of granuloma. In our case, deterioration of renal function was recovered after steroid pulse therapy.

Keyword

Microscopic polyangiitis; ANCA

MeSH Terms

Antibodies, Antineutrophil Cytoplasmic
Asthma
Biopsy
Glomerulonephritis
Granuloma
Microscopic Polyangiitis*
Purpura
Vasculitis
Antibodies, Antineutrophil Cytoplasmic