A Comparative Study of Clinical Symptoms between Pregnancy and Non-Pregnancy Groups in In Vitro Fertilization and Embryo Transfer

Park, Chan Ho; Han, Hyuck Dong; Hong, Min; Lee, Young Jin; Chung, In Bai; Cha, Dong Soo

Abstract

Following IVF and ET it is common to develop clinical symptoms according to pregnancy outcome until day of pregnancy test(post ET day 16). But surprisingly, the squalae of day-case IVF and ET have not been reported . This study was analyzed on clinical symptoms after ET between pregnancy group and non-pregnancy group in 157 IVF and ET cycles from september, 1995 to June, 1996 at the department of Obstetrics and Gynecology, Yonsei University, Wonju Christian Hospital. The results obtained were as follows : 1. The breast engorgement was reported by 36 of 46(78.3 %) of our patients in pregnancy group and 65 of 111(58.6 %) of our patients in non pregnancy group. The results of both group showed significant difference(p<0.05). In pregnancy group, highest incidence was noted at post ET day 4, which was continued until post ET day 16. In non-pregnancy group, highest incidence was noted from post ET day 4 to day 7, which diminished gradually over following 5 days and then nearly disappeared. 2. The vaginal bleeding was reported by 8 of 46(17.4 %) of our patients in pregnancy group and 35 of 111(31.5 %) of our patients in non-pregnancy group. The results of both group did not show significant difference(p>0.05). However in pregnancy group, vaginal bleeding was noted from post ET day 8, which its incidence was peaked at post ET day 10 and its pattern was vaginal spotting. In non-pregnancy group, vaginal bleeding was mens like pattern and its incidence was peaked at post ET day 15. 3. The itching sensation on vagina was reported only in pregnancy group(4.3 %) and the urticaria and itching sensation on skin was reported only in non-pregnancy group(5.4 %). The results of both group did not show significant difference(p>0.05).