Korean J Orthod.  2000 Aug;30(4):433-440.

A study of osteonectin expression patterns in BAPN-induced cleft palate formed rats

Affiliations
  • 1Department of Orthodontics, School of Dentistry, Wonkwang University, Korea.
  • 2Department of Oral Pathology, School of Dentistry, Wonkwang University, Korea.
  • 3Wonkwang Dental Institute, Wonkwang University, Korea.

Abstract

The purpose of this study was to investigate osteonectin expression patterns in cleft palatecompare to normal palate rats. We used 4 pregnant rats, and beta-aminoproprionitrile was oral dose to rat according to lg/kg body weight at gestation days 13 to induce cleft palate. Total 6 fetus was got with cleft formed, then 3 fetus was used for immunohistostain and 3 fetus was used for western blot analysis. Expression patterns of osteonectin in mesenchymal cells of cleft palate was more dilute to mesenchymal cells of normal palate with immnunohistostain, and width and length of band of maxilla in cleft palate was more thin than maxilla of normal palate with western blot study.

Keyword

Western blot; Cleft palate; Osteonectin; Immunohistostaln; Western blot

MeSH Terms

Animals
Blotting, Western
Body Weight
Cleft Palate*
Fetus
Maxilla
Osteonectin*
Palate
Pregnancy
Rats*
Osteonectin
Full Text Links
  • KJOD
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr