Korean J Urol.  2015 Jan;56(1):82-85. 10.4111/kju.2015.56.1.82.

Heart failure as the first manifestation of renal cell carcinoma

Affiliations
  • 1Department of Urology, Singapore General Hospital, Singapore. allen.sim.s.p@sgh.com.sg
  • 2Department of Cardiology, National Heart Centre Singapore, Singapore.

Abstract

We report the rare case of a patient with advanced renal cell carcinoma (RCC) who initially presented to the hospital with symptoms of cardiac failure. Preoperative cardiac studies did not reveal any underlying ischemia. After resection of a large 14-cm left renal tumor, cardiac function was noted to improve dramatically. We discuss this case of concomitant RCC and nonischemic cardiomyopathy.

Keyword

Cardiomyopathies; Heart failure; Paraneoplastic syndromes ; Renal cell carcinoma

MeSH Terms

Asian Continental Ancestry Group
Carcinoma, Renal Cell/*diagnosis/surgery
Cardiomyopathies/*diagnosis
Female
Heart Failure/*etiology
Humans
Middle Aged
Paraneoplastic Syndromes/complications
Thalassemia/complications

Figure

  • Fig. 1 Wall motion diagram of first transthoracic echocardiogram. AA, apical anterior; AI, apical inferior; AL, apical lateral; AS, apical septal; BA, basal anterior; BAL, basal anterior lateral; BAS, basal anterior septal; BI, basal inferior; BIL, basal inferior lateral; BIS, basal inferior septal; MA, mid anterior; MAL, mid anterior lateral; MAS, mid anterior septal; MI, mid inferior; MIL, mid inferior lateral; MIS, mid inferior septal.

  • Fig. 2 Transverse section of computed tomography scan of abdomen showing a left renal mass.

  • Fig. 3 Coronal section of computed tomography scan of chest/abdomen showing dilated heart chamber and left renal mass.


Reference

1. Gold PJ, Fefer A, Thompson JA. Paraneoplastic manifestations of renal cell carcinoma. Semin Urol Oncol. 1996; 14:216–222.
2. John WJ, Foon KA, Patchell RA. Paraneoplastic syndromes. In : DeVita VT, Hellman S, Rosenberg SA, editors. Cancer: principles and practice of oncology. 5th ed. Philadelphia: Lippincott-Raven;1997. p. 2397–2422.
3. Palapattu GS, Kristo B, Rajfer J. Paraneoplastic syndromes in urologic malignancy: the many faces of renal cell carcinoma. Rev Urol. 2002. 4:p. 163–170.
4. Vieira MS, Antunes N, Carvalho H, Torres S. Renal cell carcinoma presenting as a stress cardiomyopathy. Eur Heart J Cardiovasc Imaging. 2013; 14:192.
5. Felker GM, Thompson RE, Hare JM, Hruban RH, Clemetson DE, Howard DL, et al. Underlying causes and long-term survival in patients with initially unexplained cardiomyopathy. N Engl J Med. 2000; 342:1077–1084.
6. Mehta PA, Dubrey SW. High output heart failure. QJM. 2009; 102:235–241.
7. Brannon ES, Merrill AJ, Warren JV, Stead EA. The cardiac output in patients with chronic anemia as measured by the technique of right atrial catheterization. J Clin Invest. 1945; 24:332–336.
8. Akashi YJ, Goldstein DS, Barbaro G, Ueyama T. Takotsubo cardiomyopathy: a new form of acute, reversible heart failure. Circulation. 2008; 118:2754–2762.
9. Wittstein IS, Thiemann DR, Lima JA, Baughman KL, Schulman SP, Gerstenblith G, et al. Neurohumoral features of myocardial stunning due to sudden emotional stress. N Engl J Med. 2005; 352:539–548.
10. Abe Y, Kondo M, Matsuoka R, Araki M, Dohyama K, Tanio H. Assessment of clinical features in transient left ventricular apical ballooning. J Am Coll Cardiol. 2003; 41:737–742.
Full Text Links
  • KJU
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr