Korean J Med Phys.  2009 Sep;20(3):159-166.

Comparison of F-18 FDG Radioacitivity to Determine Accurate Dose Calibrator Activity Measurements

Affiliations
  • 1Department of Radiologic Science, Nambu University, Gwangju, Korea.
  • 2Department of Radiologic Science, Shinheung College University, Uijeongbu, Korea. dckweon@shc.ac.kr
  • 3Department of Nuclear Medicine, Severance Hospital, Yonsei University Medical Center, Seoul, Korea.
  • 4Heart Research Center, Chonnam National University Hospital, Gwangju, Korea.

Abstract

Obviously, the administration of the prescribed amount of activity to the patient requires proper operation of the dose calibrator, which shall be verified by implementing the required quality control on the instrument. This investigation examined the accuracy and precision of dose calibrator activity measurement of the radiopharmaceutical F-18 FDG. To investigate the status of the nuclear medicine centers in Korea for the performance of dose calibrators, 10 centers providing PET/CT system services in Korea were inspected in 2008. We measured accuracy and precision in 10 equipments in consideration of PET/CT model, installation area, and installation time. According to the results of comparative analysis of 10 dose calibrators used to measure radioactivity of F-18 FDG, accuracy was -5.00~4.50% and precision was 0.05~0.45%, satisfying the international standards, which are accuracy +/-10% and precision +/-5%. This study demonstrated that, for accurate measurements, no adjustment is necessary for a dose calibrator setting when measuring different dose calibrators of F-18 FDG activity prescriptions.

Keyword

F-18 FDG; Dose calibrator; PET/CT

MeSH Terms

Humans
Korea
Nuclear Medicine
Quality Control
Radioactivity
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