Korean J Anat.  1997 Oct;30(5):567-574.

Cytogenetic Analysis of Squamous Cell Carcinoma of the Lung

• Jo SJ

Abstract

The cytogenetic study of 3 cases of squamous cell carcinoma of the lung was performed to identify chromosomal abnormalities. All tumor cells were hypodiploid state on the average. Specicfic chromosomal anomalies were del[4][q33] and del[6][q25] in case 1, i[21q] in case 2, and del[3][q12] in case 3. The tendencies of monosomy were appered at chromosome 1, 9, 17, 18, 19, 22, and X chromosome in case 1, chromosome 22 and Y chromosome in case 2, and chromosome 1, 9, 16, 19, 20, 21, 22 and Y chromosome in case 3. The losses of sex chromosomes and chromosome 22 were common in these cases.

Keyword

Cytogenetif analysis; Chromsomal abnormality

MeSH Terms

Carcinoma, Squamous Cell*
Chromosome Aberrations
Chromosomes, Human, Pair 1
Chromosomes, Human, Pair 22
Cytogenetic Analysis*
Cytogenetics*
Lung*
Monosomy
Sex Chromosomes
X Chromosome
Y Chromosome