Korean J Anat.  1997 Oct;30(5):567-574.

Cytogenetic Analysis of Squamous Cell Carcinoma of the Lung


The cytogenetic study of 3 cases of squamous cell carcinoma of the lung was performed to identify chromosomal abnormalities. All tumor cells were hypodiploid state on the average. Specicfic chromosomal anomalies were del[4][q33] and del[6][q25] in case 1, i[21q] in case 2, and del[3][q12] in case 3. The tendencies of monosomy were appered at chromosome 1, 9, 17, 18, 19, 22, and X chromosome in case 1, chromosome 22 and Y chromosome in case 2, and chromosome 1, 9, 16, 19, 20, 21, 22 and Y chromosome in case 3. The losses of sex chromosomes and chromosome 22 were common in these cases.


Cytogenetif analysis; Chromsomal abnormality
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