Korean J Occup Environ Med.
2002 Mar;14(1):78-84.
Aluminum Clearance by Hemodialysis in Chronic Renal Failure
- Affiliations
-
- 1Department of Preventive Medicine, College of Medicine, Dong-A University, Korea. oemroad@dreamwiz.com
- 2Department of Internal Medicine, College of Medicine, Dong-A University, Korea.
- 3Department of Occupational Medicine, College of Medicine, Dong-A University, Korea.
- 4Department of Occupational and Environmental Medicine, Sam-sung Hospital, Yangsan, Korea.
Abstract
OBJECTIVES
This study was carried out to investigate aluminum levels in blood and the factors affecting aluminum concentration; we also presented findings on aluminum clearance during hemodialysis in chronic renal failure patients.
METHODS
We selected 56 patients with case of chronic renal failure and 144 healthy examinees as a control group. We analysed aluminum concentrations in their blood, water and dialysis fluid.
RESULTS
The blood aluminum concentration in the 56 patients was 2.38+/-0.27 microgram/ dL , about 4 times higher than that of the control group (p < 0.01). Blood aluminum concentrations were not affected by factors such as creatinine, BUN, hemodialysis duration, iron, and drinking water. After hemodialysis, blood aluminum level were decreased by about 15% and the aluminum concentration in the dialysis fluid was increased.
CONCLUSIONS
Blood aluminum levels were significantly high in the chronic renal failure patients; and hemodialysis helped the patients to excrete aluminum. Authors suggest that a purified dialysis fluid containing a lower aluminum concentration would facilitate aluminum excretion in hemodialysis patients.
